Alguns arquivos em PDF de estudos e Papers sobre o Verisol:

• Verisol PDF 1 – White Paper da Gelita sobre o Verisol
• Verisol PDF 2 – Peptídeos Bioativos do Colágeno Verisol para Pele
• Verisol PDF 3 – Material sobre Verisol

Veja os estudos científicos realizados para o Colágeno Verisol:

1) JOURNAL OF MEDICINAL FOOD, J Med Food 00 (0) 2015, 1–9, DOI: 10.1089/jmf.2015.0022, Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology, Michael Schunck, 1 Vivian Zague, 2 Steffen Oesser, 1 Ehrhardt Proksch, 3

2) Proksch, E., et al. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: A double-blind, placebo-controlled study. Skin Pharmacology and Physiology, v. 27, n.1, p. 47–55, 2013.

3) Oesser S, Adam M, Babel W, Seifert J: Oral administration of (14)C labeled gelatin hydrolysate leads to an accumulation of radioactivity in cartilage of mice (C57/BL).
J Nutr 1999;129:1891 – 1895.

4) Watanabe-Kamiyama M, Shimizu M, Kamiyama S, Taguchi Y, Sone H, Morimatsu F, Shirakawa H, Furukawa Y, Komai M: Absorption and effectiveness of orally administered low molecular weight collagen hydrolysate in rats. J Agric Food Chem 27-1-2010;58:835 – 841.

5) Rawlings AV, Harding CR: Moisturization and skin barrier function. Dermatol Ther 2004;17 Suppl 1:43 – 48.

6) Sandilands A, Sutherland C, Irvine AD, McLean WH: Filaggrin in the frontline: role in skin barrier function and disease. J Cell Sci 1-5-2009;122:1285 – 1294.

7) Primavera G, Berardesca E: Clinical and instrumental evaluation of a food supplement in improving skin hydration. Int J Cosmet Sci 2005;27:199 – 204.

8) Shin JE, Oh JH, Kim YK, Jung JY, Chung JH: Transcriptional regulation of proteoglycans and glycosaminoglycan chain-synthesizing glycosyltransferases by UV irradiation in cultured human dermal fibroblasts. J Korean Med Sci 2011;26:417 – 424.

9)Reinboth B, Hanssen E, Cleary EG, Gibson MA: Molecular interactions of biglycan and decorin with elastic fiber components: biglycan forms a ternary complex with tropoelastin and microfibril-associated glycoprotein 1. J Biol Chem 8-2-2002;277:3950 – 3957.

10)Proksch E, Segger D, Degwert J, Schunck M, Zague V, Oesser S: Oral Supplementation of Specific Collagen Peptides has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study. Skin Pharmacol Physiol 2014;27:47 – 55.

11) Proksch E, Schunck M, Zague V, Segger D, Degwert J, Oesser S: Oral Intake of Specic
Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis.
Skin Pharmacol Physiol 2014;27:113-119

Estudos científicos sobre outros colágenos e colágeno tipo 2

[1] BELLO, Alfonso E.; OESSER, Steffen. Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature. Current medical research and opinion, v. 22, n. 11, p. 2221-2232, 2006.

[2] Kim HK, Kim MG, Leem KH. Osteogenic Activity of Collagen Peptide via ERK/MAPK Pathway Mediated Boosting of Collagen Synthesis and Its Therapeutic Efficacy in Osteoporotic Bone by Back-Scattered Electron Imaging and Microarchitecture Analysis. Molecules, 18; 2013. p. 15474-89.

[3] Guillerminet F, Beaupied H, Fabien-Soulé V, Tomé D, Benhamou CL, Roux C, Blais A. Hydrolyzed collagen improves bone metabolism and biomechanical parameters in ovariectomized mice: An in vitro and in vivo study. Elsevier, Bone 46; 2010. p. 827–34.

[4] BENITO-RUIZ, P. et al. A randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort. International journal of food sciences and nutrition, v. 60, n. sup2, p. 99-113, 2009.

[5] Schunk M, Schulze CH, Oesser S. Collagen hydrolysate supplementation stimulates proteoglycan metabolism and gene expression of articular chondrocytes. International Cartilage Repair Society Poster 189; 2007.

[6] CLARK, Kristine L. et al. 24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. Current medical research and opinion, v. 24, n. 5, p. 1485-1496, 2008.

[7] JUHER, Teresa Figueres; PÉREZ, Esther Basés. Revisión de los efectos beneficiosos de la ingesta de colágeno hidrolizado sobre la salud osteoarticular y el envejecimiento dérmico. Nutrición Hospitalaria, v. 32, n. 1, p. 62-66, 2015.

[8] BRUYÈRE, Olivier et al. Effect of collagen hydrolysate in articular pain: A 6-month randomized, double-blind, placebo controlled study. Complementary therapies in medicine, v. 20, n. 3, p. 124-130, 2012.

Estudos sobre ácido hialurônico

1. 1.Fraser JRE. et al. Hyaluronan: its nature, distribution, functions and turnover. J Int Med, v.242, p. 27–33, 1997.
2. Cyphert JM et al. Size Matters: Molecular Weight Specificity of Hyaluronan Effects in Cell Biology. Int J Cell Biol, 2015: 56381.
3.  Kawada, C et al. Ingestion of hyaluronans (molecular weights 800 k and 300 k) improves dry skin conditions: a randomized, double blind, controlled study. J. Clin. Biochem. Nutr, v. 56, n. 1, p.66–73, 2015.
4. Yoshida T et al. Improvement of dry skin by a food containing hyaluronic acids derived from microbial fermentation. J New Rem & Clin, v. 58, n. 8, p. 143–155, 2009.
5. Kimura, M. et al. Absorption of Orally Administered Hyaluronan. Journal of Medicinal Food, v. 19, n. 12, p. 1172–1179, 2016.
6. Oe M et al. Oral hyaluronan relieves knee pain: a review., v. 15, n. 1, p. 1–10, 2016.